Periconceptional changes in thyroid function: a longitudinal study

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Periconceptional changes in thyroid function: a longitudinal study

BACKGROUND Limitations in our current knowledge of normative physiologic changes in thyroid function during the periconception window narrow our ability to establish an optimal approach to screening and diagnosis of thyroid disease in pregnant women. The objective of this study was to characterize changes in thyroid function during the transition from the pre-pregnant to pregnant state in norma...

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A longitudinal study of thyroid function in pregnancy.

We undertook a prospective longitudinal study of thyroid function in 36 pregnant women. There were significant increases in thyroxin-binding globulin, thyrotropin, and triiodothyronine. Albumin, free thyroxin (measured by an analog and a nonanalog method), and the free thyroxin index were significantly decreased. Results for the free thyroxin methods were correlated with each other in each trim...

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Thyroid Function and Body Weight: A Community-Based Longitudinal Study

OBJECTIVE Body weight and overt thyroid dysfunction are associated. Cross-sectional population-based studies have repeatedly found that thyroid hormone levels, even within the normal reference range, might be associated with body weight. However, for longitudinal data, the association is less clear. Thus, we tested the association between serum thyrotropin (TSH) and body weight in a community-b...

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Longitudinal trends in thyroid function in relation to iodine intake: ongoing changes of thyroid function despite adequate current iodine status.

OBJECTIVE Several cross-sectional studies on populations with iodine deficiency showed that TSH-levels are negatively associated with age, while in populations with high iodine intake TSH is positively associated with age. The question is whether such an age-thyroid function relation is an ongoing process apparent also in longitudinal studies and whether it reflects an actual iodine deficiency ...

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Changes in salivary gland function following radioiodine therapy of thyroid diseases: A comparison of high-dose therapy for thyroid cancer and low-dose therapy for benign thyroid disease

Introduction: High-dose radioactive iodine therapy in differentiated thyroid cancer (DTC) may adversely affect the salivary gland function. This study is aimed to evaluate the effect of radioactive iodine (RAI) with dose of 100 mCi in DTC patients compared to lower doses of less than 30 mCi in hyperthyroid cases. Methods: Fifty four patients (13 men and 41 women) age: 42.3±14.3 (21-71) years w...

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ژورنال

عنوان ژورنال: Reproductive Biology and Endocrinology

سال: 2012

ISSN: 1477-7827

DOI: 10.1186/1477-7827-10-20